Journey of a Matrikine® into the skin
MATRIKINES The key to anti-ageing
In 1999, the French Professor, François-Xavier Maquart and his team published their first article mentioning Matrikine®.
Matrikines® are peptides, derived from the surrounding extracellular matrix. These particular peptides act like messengers to other cells, that start the repair process within the tissue matrix, hence the name.
When a Matrikine® peptide is recognised by a cell membrane receptor and binds to that receptor, it triggers intracellular action that:
- Promotes tissue repair
- Helps with wound healing
- Stimulates macromolecule synthesis
Since 1999, a huge number of different Matrikines® have been identified. Some with very specialised functions like the stimulation of collagen and fibronectin synthesis in the skin.
These are the kind of peptides Sederma has been developing for their anti-ageing properties. It’s these Matrikines® you’ll find in the Matrixyl® range.
 MAQUART FX. et al, 1999, Régulation de l’activité cellulaire par la matrice extracellulaire : le concept de Matrikines, Journal de la Société de Biologie, 193, (4), p 423.
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